Sildenafil was unfavorable in in vitro bacterial and Chinese hamster ovary cell assays to detect mutagenicity, and in vitro human lymphocytes and in vivo mouse micronucleus assays to detect clastogenicity.Results of Other Medications on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (major route) and CYP2C9 (slight route). Hence, in